智能生物学实验室（IBLab）

@article{yuan2025nrp2,
  title = {Re-examining interneuron-specific Nrp2 deletion: overlooked striatal and cortical contributions},
  author = {Yuan, AiHua and Yuan, Bo},
  journal = {Molecular Psychiatry},
  year = {2025},
  note = {Accepted},
  doi = {10.1038/s41380-025-03309-1},
}

@article{han2025rna,
  title = {Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins},
  author = {Han, WenJian and Yuan, Bo and Fan, XiaoJuan and Li, WeiKe and Yuan, YiTing and Zhang, YueFang and Wang, Shu and Shan, ShiFang and Hafner, Markus and Wang, ZeFeng and Qiu, ZiLong},
  journal = {Nature Communications},
  year = {2025},
  note = {Accepted},
  doi = {10.1038/s41467-025-57388-0},
}

@article{li2025wholebrain,
  title = {Whole-brain in vivo base editing reverses behavioral changes in Mef2c-mutant mice},
  author = {Li, WeiKe and Zhang, ShuQian and Peng, WanLing and Shi, YuHan and Yuan, Bo and Yuan, YiTing and Xue, ZhenYu and Wang, JinCheng and Han, WenJian and Chen, ZhiFang and Shan, ShiFang and Xue, BiQing and Chen, JinLong and Zhang, Cheng and Zhu, ShuJia and Tai, YiLin and Cheng, Tian-Lin and Qiu, ZiLong},
  journal = {Nature Neuroscience},
  volume = {27},
  pages = {116--128},
  year = {2025},
  doi = {10.1038/s41593-023-01499-x},
}

@article{yuan2023denovo,
  title = {Identification of de novo mutations in the Chinese ASD cohort via whole-exome sequencing unveils brain regions implicated in autism},
  author = {Yuan, Bo and Wang, MengDi and Wu, XinRan and Cheng, PeiPei and Zhang, Ran and Zhang, Ran and Yu, ShunYing and Zhang, Jie and Du, YaSong and Wang, XiaoQun and Qiu, ZiLong},
  journal = {Neuroscience Bulletin},
  volume = {39},
  number = {10},
  pages = {1469--1480},
  year = {2023},
  doi = {10.1007/s12264-023-01112-0},
}

@article{yuan2023cytosine,
  title = {Engineering of cytosine base editors with genotoxicity minimization and editing scope diversification},
  author = {Yuan, Bo and Zhang, ShuQian and Song, LiTing and Chen, JinLong and Cao, JiXin and Qiu, JiaYi and Qiu, ZiLong and Chen, JingQi and Zhao, Xing-Ming and Cheng, Tian-Lin},
  journal = {Nucleic Acids Research},
  volume = {51},
  number = {20},
  pages = {e105},
  year = {2023},
  doi = {10.1093/nar/gkad842},
}

@article{zhang2023tada1,
  title = {TadA orthologs enable both cytosine and adenine editing of base editors},
  author = {Zhang, ShuQian and Yuan, Bo and Cao, JiXin and Chen, JinLong and Qiu, JiaYi and Song, LiTing and Qiu, ZiLong and Zhao, Xing-Ming and Chen, JingQi and Cheng, Tian-Lin},
  journal = {Nature Communications},
  volume = {14},
  pages = {414},
  year = {2023},
  doi = {10.1038/s41467-023-36161-z},
}

@article{zhang2023tada2,
  title = {TadA reprogramming to generate potent miniature base editors with high precision},
  author = {Zhang, ShuQian and Song, LiTing and Yuan, Bo and Zhang, Cheng and Cao, JiXin and Chen, JinLong and Qiu, JiaYi and Tai, YiLin and Chen, JingQi and Qiu, ZiLong and Zhao, Xing-Ming and Cheng, Tian-Lin},
  journal = {Nature Communications},
  volume = {14},
  pages = {413},
  year = {2023},
  doi = {10.1038/s41467-023-36160-0},
}

@article{cheng2022il1rap,
  title = {Novel IL1RAP mutation associated with schizophrenia interferes with neuronal growth and related NF-κB signal pathways},
  author = {Cheng, PeiPei and Zhang, Ran and Shan, ShiFang and Yuan, Bo and Chen, JinLong and Qiu, ZiLong and Du, YaSong},
  journal = {Neuroscience Letters},
  volume = {775},
  pages = {136533},
  year = {2022},
  doi = {10.1016/j.neulet.2022.136533},
}

@article{zhou2022chmp4c,
  title = {Identification of CHMP4C as a new risk gene for inherited dilated cardiomyopathy},
  author = {Zhou, NianWei and Tang, Lu and Jiang, YingYing and Li, XueJie and Shan, ShiFang and Yuan, Bo and Qin, ShengMei and Pan, CuiZhen and Wang, XiaoLin and Shu, XianHong and Qiu, ZiLong and Ge, JunBo},
  journal = {Journal of Genetics and Genomics},
  volume = {49},
  pages = {169--172},
  year = {2022},
  doi = {10.1016/j.jgg.2021.12.003},
}

@article{zhang2021chd7,
  title = {An intronic variant of CHD7 identified in autism patients interferes with neuronal differentiation and development},
  author = {Zhang, Ran and He, Hui and Yuan, Bo and Wu, ZiYan and Wang, XiuZheng and Du, YaSong and Chen, YueJun and Qiu, ZiLong},
  journal = {Neuroscience Bulletin},
  volume = {37},
  number = {8},
  pages = {1091--1106},
  year = {2021},
  doi = {10.1007/s12264-021-00683-1},
}

@article{sun2020mecp2,
  title = {Visualization and correction of social abnormalities-associated neural ensembles in adult MECP2 duplication mice},
  author = {Sun, Le and Chen, RuiGuo and Li, Long and Yuan, Bo and Song, Kun and Pan, Na and Cheng, Tian-Lin and Chang, ShiYang and Lin, KunZhang and He, XiaoBin and Wu, Qian and Xu, FuQiang and Qiu, ZiLong and Wang, XiaoQun},
  journal = {Science Bulletin},
  volume = {65},
  number = {14},
  pages = {1192--1202},
  year = {2020},
  doi = {10.1016/j.scib.2020.03.026},
}

@article{yu2020mecp2,
  title = {Reversal of social recognition deficit in adult mice with MECP2 duplication via normalization of MeCP2 in the medial prefrontal cortex},
  author = {Yu, Bin and Yuan, Bo and Dai, Jian-Kun and Cheng, Tian-Lin and Xia, Sheng-Nan and He, Ling-Jie and Yuan, Yi-Ting and Zhang, Yue-Fang and Xu, Hua-Tai and Xu, Fu-Qiang and Liang, Zhi-Feng and Qiu, Zi-Long},
  journal = {Neuroscience Bulletin},
  volume = {36},
  number = {6},
  pages = {570--584},
  year = {2020},
  doi = {10.1007/s12264-020-00467-w},
}

@article{li2020cas9,
  title = {Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination},
  author = {Li, Shuo and Yuan, Bo and Cao, JiXin and Chen, JingQi and Chen, JinLong and Qiu, JiaYi and Zhao, Xing-Ming and Wang, XiaoLin and Qiu, ZiLong and Cheng, Tian-Lin},
  journal = {Nature Communications},
  volume = {11},
  pages = {5827},
  year = {2020},
  doi = {10.1038/s41467-020-19730-9},
}

@article{cheng2019ct,
  title = {Expanding C-T base editing toolkit with diversified cytidine deaminases},
  author = {Cheng, Tian-Lin and Li, Shuo and Yuan, Bo and Wang, XiaoLin and Zhou, WenHao and Qiu, ZiLong},
  journal = {Nature Communications},
  volume = {10},
  pages = {3612},
  year = {2019},
  doi = {10.1038/s41467-019-11562-6},
}

@article{qiu2019autism,
  title = {Towards the framework of understanding autism spectrum disorders},
  author = {Qiu, ZiLong and Yuan, Bo},
  journal = {Neuroscience Bulletin},
  volume = {35},
  number = {6},
  pages = {1110--1112},
  year = {2019},
  doi = {10.1007/s12264-019-00443-z},
}

@article{yang2017mir505,
  title = {Mir505-3p regulates axonal development via inhibiting the autophagy pathway by targeting Atg12},
  author = {Yang, Kan and Yu, Bin and Cheng, Cheng and Cheng, TianLin and Yuan, Bo and Li, Kai and Xiao, JunHua and Qiu, ZiLong and Zhou, YuXun},
  journal = {Autophagy},
  volume = {13},
  number = {10},
  pages = {1679--1696},
  year = {2017},
  doi = {10.1080/15548627.2017.1353841},
}

@article{che2017nscs,
  title = {Accumulated quiescent neural stem cells in adult hippocampus of the mouse model for the MECP2 duplication syndrome},
  author = {Che, ZhiFang and Li, Xiao and Zhou, JingJing and Yuan, Bo and Yu, Bin and Tong, DaLi and Cheng, Cheng and Shao, YinQi and Xia, ShengNan and Zhang, Ran and Lyu, JingWen and Yu, XiuYa and Dong, Chen and Zhou, Wen-Hao and Qiu, ZiLong},
  journal = {Scientific Reports},
  volume = {7},
  pages = {41701},
  year = {2017},
  doi = {10.1038/srep41701},
}

@article{yuan2017fgf13,
  title = {Autism-related protein MeCP2 regulates FGF13 expression and emotional behaviors},
  author = {Yuan, Bo and Cheng, Tian-Lin and Yang, Kan and Zhang, Xu and Qiu, ZiLong},
  journal = {Journal of Genetics and Genomics},
  volume = {44},
  number = {1},
  pages = {63--66},
  year = {2017},
  doi = {10.1016/j.jgg.2016.10.004},
}

@article{lyu2016reciprocal,
  title = {Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs},
  author = {Lyu, Jing-Wen and Yuan, Bo and Cheng, Tian-Lin and Qiu, Zi-Long and Zhou, Wen-Hao},
  journal = {Scientific Reports},
  volume = {6},
  pages = {20392},
  year = {2016},
  doi = {10.1038/srep20392},
}

@article{xin2015tet1,
  title = {Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress},
  author = {Xin, Yong-Juan and Yuan, Bo and Yu, Bin and Wang, Yu-Qing and Wu, Jia-Jia and Zhou, Wen-Hao and Qiu, ZiLong},
  journal = {Scientific Reports},
  volume = {5},
  pages = {7645},
  year = {2015},
  doi = {10.1038/srep07645},
}

@article{wilke2012neurod2,
  title = {NeuroD2 regulates the development of hippocampal mossy fiber synapses},
  author = {Wilke, Scott A and Hall, Benjamin J and Antonios, Joseph K and DeNardo, Laura A and Otto, Stefanie and Yuan, Bo and Chen, Fading and Robbins, Elissa M and Tiglio, Katie and Williams, Megan E and Qiu, ZiLong and Biederer, Thomas and Ghosh, Anirvan},
  journal = {Neural Development},
  volume = {7},
  pages = {9},
  year = {2012},
  doi = {10.1186/1749-8104-7-9},
}