@article{han2025rna,title={Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins},author={Han, WenJian and Yuan, Bo and Fan, XiaoJuan and Li, WeiKe and Yuan, YiTing and Zhang, YueFang and Wang, Shu and Shan, ShiFang and Hafner, Markus and Wang, ZeFeng and Qiu, ZiLong},journal={Nature Communications},year={2025},note={Accepted},doi={10.1038/s41467-025-57388-0},}
Whole-brain in vivo base editing reverses behavioral changes in Mef2c-mutant mice
WeiKe Li, ShuQian Zhang, WanLing Peng, and 15 more authors
@article{li2025wholebrain,title={Whole-brain in vivo base editing reverses behavioral changes in Mef2c-mutant mice},author={Li, WeiKe and Zhang, ShuQian and Peng, WanLing and Shi, YuHan and Yuan, Bo and Yuan, YiTing and Xue, ZhenYu and Wang, JinCheng and Han, WenJian and Chen, ZhiFang and Shan, ShiFang and Xue, BiQing and Chen, JinLong and Zhang, Cheng and Zhu, ShuJia and Tai, YiLin and Cheng, Tian-Lin and Qiu, ZiLong},journal={Nature Neuroscience},volume={27},pages={116--128},year={2025},doi={10.1038/s41593-023-01499-x},}
2023
Identification of de novo mutations in the Chinese ASD cohort via whole-exome sequencing unveils brain regions implicated in autism
Bo Yuan, MengDi Wang, XinRan Wu, and 8 more authors
@article{yuan2023denovo,title={Identification of de novo mutations in the Chinese ASD cohort via whole-exome sequencing unveils brain regions implicated in autism},author={Yuan, Bo and Wang, MengDi and Wu, XinRan and Cheng, PeiPei and Zhang, Ran and Zhang, Ran and Yu, ShunYing and Zhang, Jie and Du, YaSong and Wang, XiaoQun and Qiu, ZiLong},journal={Neuroscience Bulletin},volume={39},number={10},pages={1469--1480},year={2023},doi={10.1007/s12264-023-01112-0},}
Engineering of cytosine base editors with genotoxicity minimization and editing scope diversification
Bo Yuan, ShuQian Zhang, LiTing Song, and 7 more authors
@article{yuan2023cytosine,title={Engineering of cytosine base editors with genotoxicity minimization and editing scope diversification},author={Yuan, Bo and Zhang, ShuQian and Song, LiTing and Chen, JinLong and Cao, JiXin and Qiu, JiaYi and Qiu, ZiLong and Chen, JingQi and Zhao, Xing-Ming and Cheng, Tian-Lin},journal={Nucleic Acids Research},volume={51},number={20},pages={e105},year={2023},doi={10.1093/nar/gkad842},}
TadA orthologs enable both cytosine and adenine editing of base editors
ShuQian Zhang, Bo Yuan, JiXin Cao, and 7 more authors
@article{zhang2023tada1,title={TadA orthologs enable both cytosine and adenine editing of base editors},author={Zhang, ShuQian and Yuan, Bo and Cao, JiXin and Chen, JinLong and Qiu, JiaYi and Song, LiTing and Qiu, ZiLong and Zhao, Xing-Ming and Chen, JingQi and Cheng, Tian-Lin},journal={Nature Communications},volume={14},pages={414},year={2023},doi={10.1038/s41467-023-36161-z},}
TadA reprogramming to generate potent miniature base editors with high precision
ShuQian Zhang, LiTing Song, Bo Yuan, and 9 more authors
@article{zhang2023tada2,title={TadA reprogramming to generate potent miniature base editors with high precision},author={Zhang, ShuQian and Song, LiTing and Yuan, Bo and Zhang, Cheng and Cao, JiXin and Chen, JinLong and Qiu, JiaYi and Tai, YiLin and Chen, JingQi and Qiu, ZiLong and Zhao, Xing-Ming and Cheng, Tian-Lin},journal={Nature Communications},volume={14},pages={413},year={2023},doi={10.1038/s41467-023-36160-0},}
2022
Novel IL1RAP mutation associated with schizophrenia interferes with neuronal growth and related NF-κB signal pathways
PeiPei Cheng, Ran Zhang, ShiFang Shan, and 4 more authors
@article{cheng2022il1rap,title={Novel IL1RAP mutation associated with schizophrenia interferes with neuronal growth and related NF-κB signal pathways},author={Cheng, PeiPei and Zhang, Ran and Shan, ShiFang and Yuan, Bo and Chen, JinLong and Qiu, ZiLong and Du, YaSong},journal={Neuroscience Letters},volume={775},pages={136533},year={2022},doi={10.1016/j.neulet.2022.136533},}
Identification of CHMP4C as a new risk gene for inherited dilated cardiomyopathy
NianWei Zhou, Lu Tang, YingYing Jiang, and 9 more authors
@article{zhou2022chmp4c,title={Identification of CHMP4C as a new risk gene for inherited dilated cardiomyopathy},author={Zhou, NianWei and Tang, Lu and Jiang, YingYing and Li, XueJie and Shan, ShiFang and Yuan, Bo and Qin, ShengMei and Pan, CuiZhen and Wang, XiaoLin and Shu, XianHong and Qiu, ZiLong and Ge, JunBo},journal={Journal of Genetics and Genomics},volume={49},pages={169--172},year={2022},doi={10.1016/j.jgg.2021.12.003},}
2021
An intronic variant of CHD7 identified in autism patients interferes with neuronal differentiation and development
@article{zhang2021chd7,title={An intronic variant of CHD7 identified in autism patients interferes with neuronal differentiation and development},author={Zhang, Ran and He, Hui and Yuan, Bo and Wu, ZiYan and Wang, XiuZheng and Du, YaSong and Chen, YueJun and Qiu, ZiLong},journal={Neuroscience Bulletin},volume={37},number={8},pages={1091--1106},year={2021},doi={10.1007/s12264-021-00683-1},}
2020
Visualization and correction of social abnormalities-associated neural ensembles in adult MECP2 duplication mice
@article{sun2020mecp2,title={Visualization and correction of social abnormalities-associated neural ensembles in adult MECP2 duplication mice},author={Sun, Le and Chen, RuiGuo and Li, Long and Yuan, Bo and Song, Kun and Pan, Na and Cheng, Tian-Lin and Chang, ShiYang and Lin, KunZhang and He, XiaoBin and Wu, Qian and Xu, FuQiang and Qiu, ZiLong and Wang, XiaoQun},journal={Science Bulletin},volume={65},number={14},pages={1192--1202},year={2020},doi={10.1016/j.scib.2020.03.026},}
Reversal of social recognition deficit in adult mice with MECP2 duplication via normalization of MeCP2 in the medial prefrontal cortex
@article{yu2020mecp2,title={Reversal of social recognition deficit in adult mice with MECP2 duplication via normalization of MeCP2 in the medial prefrontal cortex},author={Yu, Bin and Yuan, Bo and Dai, Jian-Kun and Cheng, Tian-Lin and Xia, Sheng-Nan and He, Ling-Jie and Yuan, Yi-Ting and Zhang, Yue-Fang and Xu, Hua-Tai and Xu, Fu-Qiang and Liang, Zhi-Feng and Qiu, Zi-Long},journal={Neuroscience Bulletin},volume={36},number={6},pages={570--584},year={2020},doi={10.1007/s12264-020-00467-w},}
Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination
@article{li2020cas9,title={Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination},author={Li, Shuo and Yuan, Bo and Cao, JiXin and Chen, JingQi and Chen, JinLong and Qiu, JiaYi and Zhao, Xing-Ming and Wang, XiaoLin and Qiu, ZiLong and Cheng, Tian-Lin},journal={Nature Communications},volume={11},pages={5827},year={2020},doi={10.1038/s41467-020-19730-9},}
2019
Expanding C-T base editing toolkit with diversified cytidine deaminases
Tian-Lin Cheng, Shuo Li, Bo Yuan, and 3 more authors
@article{cheng2019ct,title={Expanding C-T base editing toolkit with diversified cytidine deaminases},author={Cheng, Tian-Lin and Li, Shuo and Yuan, Bo and Wang, XiaoLin and Zhou, WenHao and Qiu, ZiLong},journal={Nature Communications},volume={10},pages={3612},year={2019},doi={10.1038/s41467-019-11562-6},}
Towards the framework of understanding autism spectrum disorders
@article{qiu2019autism,title={Towards the framework of understanding autism spectrum disorders},author={Qiu, ZiLong and Yuan, Bo},journal={Neuroscience Bulletin},volume={35},number={6},pages={1110--1112},year={2019},doi={10.1007/s12264-019-00443-z},}
2017
Mir505-3p regulates axonal development via inhibiting the autophagy pathway by targeting Atg12
@article{yang2017mir505,title={Mir505-3p regulates axonal development via inhibiting the autophagy pathway by targeting Atg12},author={Yang, Kan and Yu, Bin and Cheng, Cheng and Cheng, TianLin and Yuan, Bo and Li, Kai and Xiao, JunHua and Qiu, ZiLong and Zhou, YuXun},journal={Autophagy},volume={13},number={10},pages={1679--1696},year={2017},doi={10.1080/15548627.2017.1353841},}
Accumulated quiescent neural stem cells in adult hippocampus of the mouse model for the MECP2 duplication syndrome
ZhiFang Che, Xiao Li, JingJing Zhou, and 12 more authors
@article{che2017nscs,title={Accumulated quiescent neural stem cells in adult hippocampus of the mouse model for the MECP2 duplication syndrome},author={Che, ZhiFang and Li, Xiao and Zhou, JingJing and Yuan, Bo and Yu, Bin and Tong, DaLi and Cheng, Cheng and Shao, YinQi and Xia, ShengNan and Zhang, Ran and Lyu, JingWen and Yu, XiuYa and Dong, Chen and Zhou, Wen-Hao and Qiu, ZiLong},journal={Scientific Reports},volume={7},pages={41701},year={2017},doi={10.1038/srep41701},}
Autism-related protein MeCP2 regulates FGF13 expression and emotional behaviors
Bo Yuan, Tian-Lin Cheng, Kan Yang, and 2 more authors
@article{yuan2017fgf13,title={Autism-related protein MeCP2 regulates FGF13 expression and emotional behaviors},author={Yuan, Bo and Cheng, Tian-Lin and Yang, Kan and Zhang, Xu and Qiu, ZiLong},journal={Journal of Genetics and Genomics},volume={44},number={1},pages={63--66},year={2017},doi={10.1016/j.jgg.2016.10.004},}
2016
Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs
Jing-Wen Lyu, Bo Yuan, Tian-Lin Cheng, and 2 more authors
@article{lyu2016reciprocal,title={Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs},author={Lyu, Jing-Wen and Yuan, Bo and Cheng, Tian-Lin and Qiu, Zi-Long and Zhou, Wen-Hao},journal={Scientific Reports},volume={6},pages={20392},year={2016},doi={10.1038/srep20392},}
2015
Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress
Yong-Juan Xin, Bo Yuan, Bin Yu, and 4 more authors
@article{xin2015tet1,title={Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress},author={Xin, Yong-Juan and Yuan, Bo and Yu, Bin and Wang, Yu-Qing and Wu, Jia-Jia and Zhou, Wen-Hao and Qiu, ZiLong},journal={Scientific Reports},volume={5},pages={7645},year={2015},doi={10.1038/srep07645},}
2012
NeuroD2 regulates the development of hippocampal mossy fiber synapses
Scott A Wilke, Benjamin J Hall, Joseph K Antonios, and 10 more authors
@article{wilke2012neurod2,title={NeuroD2 regulates the development of hippocampal mossy fiber synapses},author={Wilke, Scott A and Hall, Benjamin J and Antonios, Joseph K and DeNardo, Laura A and Otto, Stefanie and Yuan, Bo and Chen, Fading and Robbins, Elissa M and Tiglio, Katie and Williams, Megan E and Qiu, ZiLong and Biederer, Thomas and Ghosh, Anirvan},journal={Neural Development},volume={7},pages={9},year={2012},doi={10.1186/1749-8104-7-9},}